Local Anesthetics: Advances, Drug Interactions and Drug Allergy

Friday, April 10, 2020 from 9AM - 12PM
The registration period has closed for this event.


Local Anesthesia is the procedure most frequently associated with adverse events in the dental office. Administration of local anesthesia containing vasoconstrictors can cause serious interactions with several different groups of medications commonly taken by patients. Dr. Sims will identify the interacting medications, explain the reasons for the interactions and the potential adverse consequences of the interactions. She will explain strategies to minimize or prevent the interactions. In addition, Dr. Sims will review allergic reactions to local anesthesia and discuss emerging concerns including allergies to newer local anesthetic options. Dr. Sims will also discuss the use of local anesthetic options to reduce opioid requirements in the management of acute pain.


At the conclusion of this course the participant should be able to

  1. Identify the components of local anesthesia most likely to cause adverse drug effects or drug interactions.
  2. Identify groups of medications with important interactions with local anesthesia.
  3. Describe the mechanism of the interaction and the impact on the patient's health.
  4. Understand strategies to reduce or avoid adverse effects or drug interactions with local anesthesia.
  5. Describe and understand the prevalence of allergic reactions to local anesthetics.
  6. Identify newer local anesthetics and their place in patient care for local anesthesia and pain management.
  7. Identify other adverse events associated with local anesthesia.


Pamela J. Sims, Pharm.D., Ph.D.

Dr. Sims earned her B.S. Pharmacy from the University of Florida, her Doctor of Pharmacy degree from Mercer University and her Ph.D. in Pharmaceutical Sciences from the University of Colorado at Boulder.

Dr. Sims recently retired as Professor of Pharmacokinetics in the Department of Pharmaceutical, Social and Administrative Sciences at Samford University McWhorter School of Pharmacy (SUMSOP) where she also coordinated and lectured in pharmacology courses for the Nurse Anesthesia, Nurse Practitioner and Physical Therapy programs.

Prior to Samford, she served on the faculty of Idaho State University.

Dr. Sims holds a faculty appointment in the University of Alabama at Birmingham School of Dentistry Department of Pediatrics where she provides lectures in Pharmacology to the Post-doctoral Dental Residents and has provided courses to the residents and the Part II Board Review in Pharmacology to D4 students as well as lectures to D3 and D4 students.

Dr. Sims publishes and lectures nationally and internationally concerning topics on Dental Pharmacology, Clinical Pharmacokinetics, Clinical Pharmacology and Pedagogy.

About Us
The University of Alabama at Birmingham School of Dentistry is an ADA CERP Recognized Provider - 11/01/2017 - 12/31/2021.


Dentist - $30

Auxiliary - $30


Registration open through 4/9/2020 10:59 PM EST

Continuing Education

3 CE Hours

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